AirHint found the following cheapest return flights from Pittsburgh (PIT) to Rome (FCO) in September 2025 (see full year).

Return flights

29 Sep - 08 Oct	jetBlue
19 Sep - 30 Sep	jetBlue
18 Sep - 25 Sep	Icelandair
02 Sep - 09 Sep	United
09 Sep - 16 Sep	United
30 Sep - 07 Oct	United
24 Sep - 01 Oct	United
04 Sep - 11 Sep	Icelandair
15 Sep - 22 Sep	United
12 Sep - 19 Sep	United
21 Sep - 28 Sep	United
06 Sep - 13 Sep	United
27 Sep - 04 Oct	United

Also check the deals for one-way flights from Pittsburgh to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Pittsburgh to Rome in September from $505

Return flights