AirHint found the following cheapest return flights from Pittsburgh (PIT) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

18 Oct - 31 Oct	Spirit Airlines
20 Oct - 31 Oct	Spirit Airlines
18 Oct - 20 Oct	Spirit Airlines
19 Oct - 31 Oct	Spirit Airlines
06 Oct - 20 Oct	Spirit Airlines
18 Oct - 03 Nov	Spirit Airlines
20 Oct - 03 Nov	Spirit Airlines
19 Oct - 20 Oct	Spirit Airlines
19 Oct - 03 Nov	Spirit Airlines
18 Oct - 04 Nov	Spirit Airlines
20 Oct - 04 Nov	Spirit Airlines
25 Oct - 08 Nov	Spirit Airlines
19 Oct - 04 Nov	Spirit Airlines

Also check the deals for one-way flights from Pittsburgh to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Pittsburgh to Rio Negro in October from $228

Return flights