AirHint found the following cheapest return flights from Palermo (PMO) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

18 Sep - 02 Oct	Lufthansa
18 Sep - 01 Oct	SWISS
09 Sep - 21 Sep	Ryanair
15 Sep - 02 Oct	Lufthansa
23 Sep - 16 Oct	Vueling Airlines
18 Sep - 04 Oct	Lufthansa
23 Sep - 04 Oct	Vueling Airlines
23 Sep - 07 Oct	Vueling Airlines
23 Sep - 10 Oct	Vueling Airlines
11 Sep - 24 Sep	ITA Airways
11 Sep - 26 Sep	ITA Airways
23 Sep - 09 Oct	Vueling Airlines
22 Sep - 08 Oct	SWISS
09 Sep - 23 Sep	Vueling Airlines
09 Sep - 27 Sep	Vueling Airlines
09 Sep - 26 Sep	SWISS
01 Sep - 18 Sep	Lufthansa
14 Sep - 26 Sep	SWISS
03 Sep - 18 Sep	ITA Airways
11 Sep - 18 Sep	ITA Airways

Also check the deals for one-way flights from Palermo to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Sao Paulo in September from $822

Return flights