Cheapest return flights from Palermo to Istanbul in October from $238

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in October 2025 (see full year).

Return flights

11 Oct - 18 Oct ITA Airways
13 Oct - 19 Oct ITA Airways
08 Oct - 12 Oct Ryanair
24 Oct - 29 Oct Turkish Airlines direct
20 Oct - 23 Oct Ryanair
20 Oct - 24 Oct Ryanair
22 Oct - 26 Oct Ryanair
16 Oct - 22 Oct Turkish Airlines direct
03 Oct - 06 Oct Turkish Airlines direct
20 Oct - 23 Oct Turkish Airlines direct

Also check the deals for one-way flights from Palermo to Istanbul in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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