Cheapest return flights from Palermo to Istanbul in December from $250

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in December 2025 (see full year).

Return flights

01 Dec - 05 Dec Ryanair
02 Dec - 05 Dec Ryanair
04 Dec - 09 Dec Ryanair
01 Dec - 08 Dec Turkish Airlines direct
01 Dec - 05 Dec Turkish Airlines direct
05 Dec - 08 Dec Turkish Airlines direct
24 Dec - 29 Dec Turkish Airlines direct
24 Dec - 28 Dec Turkish Airlines direct
08 Dec - 12 Dec Turkish Airlines
31 Dec - 04 Jan Turkish Airlines direct
08 Dec - 12 Dec Turkish Airlines direct
30 Dec - 04 Jan Ryanair

Also check the deals for one-way flights from Palermo to Istanbul in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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