Cheapest return flights from Palermo to Istanbul in April from $293

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in April 2026 (see full year).

Return flights

12 Apr - 15 Apr Turkish Airlines direct
19 Apr - 22 Apr Turkish Airlines direct
16 Apr - 19 Apr Lufthansa
26 Apr - 29 Apr Turkish Airlines direct
29 Apr - 04 May Turkish Airlines direct
10 Apr - 17 Apr Turkish Airlines direct
03 Apr - 08 Apr Transavia France
22 Apr - 26 Apr easyJet
17 Apr - 19 Apr Ryanair
30 Apr - 04 May Turkish Airlines direct
23 Apr - 26 Apr Vueling Airlines
02 Apr - 06 Apr Ryanair

Also check the deals for one-way flights from Palermo to Istanbul in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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