AirHint found the following cheapest return flights from Palermo (PMO) to Prague (PRG) in April 2026 (see full year).

Return flights

18 Apr - 22 Apr	Ryanair
25 Apr - 28 Apr	Ryanair
16 Apr - 19 Apr	Ryanair
23 Apr - 28 Apr	SWISS
16 Apr - 23 Apr	Ryanair
09 Apr - 14 Apr	Ryanair
22 Apr - 01 May	easyJet
03 Apr - 05 Apr	Ryanair
28 Apr - 01 May	easyJet
03 Apr - 08 Apr	Ryanair
29 Apr - 04 May	SWISS
29 Apr - 02 May	SWISS
01 Apr - 05 Apr	Ryanair
13 Apr - 17 Apr	Ryanair
28 Apr - 03 May	Austrian Airlines
29 Apr - 03 May	SWISS
28 Apr - 07 May	Vueling Airlines
30 Apr - 03 May	Lufthansa
30 Apr - 04 May	Lufthansa
28 Apr - 10 May	Vueling Airlines

Also check the deals for one-way flights from Palermo to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Prague in April from $142

Return flights