AirHint found the following cheapest return flights from Prague (PRG) to Boston (BOS) in October 2025 (see full year).

Return flights

06 Oct - 12 Oct	Condor
09 Oct - 14 Oct	Condor
02 Oct - 05 Oct	Condor
09 Oct - 12 Oct	Condor
05 Oct - 12 Oct	Condor
12 Oct - 19 Oct	Condor
15 Oct - 19 Oct	Eurowings
23 Oct - 30 Oct	Ryanair
02 Oct - 18 Oct	Aer Lingus
14 Oct - 17 Oct	Condor
31 Oct - 09 Nov	Scandinavian Airlines
18 Oct - 01 Nov	Turkish Airlines

Also check the deals for one-way flights from Prague to Boston in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Boston in October from $442

Return flights