AirHint found the following cheapest return flights from Prague (PRG) to Cape Town (CPT) in September 2025 (see full year).

Return flights

11 Sep - 24 Sep	Condor
15 Sep - 28 Sep	Condor
20 Sep - 03 Oct	Condor
25 Sep - 28 Oct	Condor
12 Sep - 28 Oct	Smart Wings
25 Sep - 27 Oct	Pegasus Airlines
17 Sep - 28 Oct	Pegasus Airlines
23 Sep - 14 Oct	Condor
16 Sep - 28 Oct	Pegasus Airlines
28 Sep - 05 Oct	EgyptAir
26 Sep - 28 Oct	Flynas
23 Sep - 10 Oct	Condor
06 Sep - 12 Sep	KLM
05 Sep - 12 Sep	KLM
08 Sep - 13 Sep	KLM
07 Sep - 11 Sep	Emirates

Also check the deals for one-way flights from Prague to Cape Town in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Cape Town

Cheap car rent in Cape Town

Cheapest return flights from Prague to Cape Town in September from $665

Return flights