AirHint found the following cheapest return flights from Prague (PRG) to Frankfurt (FRA) in September 2025 (see full year).

Return flights

10 Sep - 11 Sep	Condor	direct
26 Sep - 28 Sep	Condor	direct
26 Sep - 29 Sep	Condor	direct
20 Sep - 24 Sep	Condor	direct
27 Sep - 01 Oct	Condor	direct
25 Sep - 28 Sep	Wizz Air UK
16 Sep - 17 Sep	Ryanair
05 Sep - 07 Sep	Condor	direct
05 Sep - 08 Sep	Condor	direct
17 Sep - 25 Sep	Condor	direct
25 Sep - 28 Sep	Condor	direct
28 Sep - 02 Oct	Condor	direct
29 Sep - 03 Oct	Condor	direct
30 Sep - 03 Oct	Condor	direct
28 Sep - 03 Oct	Condor	direct

Also check the deals for one-way flights from Prague to Frankfurt in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Frankfurt in September from $156

Return flights