AirHint found the following cheapest return flights from Prague (PRG) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

11 Dec - 15 Jan	Turkish Airlines
24 Dec - 11 Jan	Turkish Airlines
18 Dec - 15 Jan	Turkish Airlines
01 Dec - 01 Dec	SWISS
20 Dec - 02 Jan	Turkish Airlines
23 Dec - 03 Jan	Smart Wings
22 Dec - 03 Jan	Turkish Airlines
21 Dec - 03 Jan	Turkish Airlines
15 Dec - 21 Jan	Condor

Also check the deals for one-way flights from Prague to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Prague to Sao Paulo in December from $1018

Return flights