Cheapest return flights from Prague to Istanbul in September from $183

Best time to book flights for Prague (PRG) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Prague (PRG) to Istanbul (IST) in September 2025 (see full year).

Return flights

20 Sep - 27 Sep Pegasus Airlines direct
01 Sep - 13 Sep Pegasus Airlines direct
12 Sep - 19 Sep Pegasus Airlines direct
30 Sep - 06 Oct Wizz Air Malta
30 Sep - 06 Oct Pegasus Airlines direct
23 Sep - 26 Sep Pegasus Airlines direct
19 Sep - 22 Sep Pegasus Airlines
08 Sep - 12 Sep Pegasus Airlines direct
17 Sep - 21 Sep Pegasus Airlines direct
19 Sep - 21 Sep Pegasus Airlines direct
25 Sep - 02 Oct Pegasus Airlines direct
06 Sep - 10 Sep Pegasus Airlines direct
15 Sep - 19 Sep Pegasus Airlines direct
10 Sep - 01 Oct SKY express
17 Sep - 03 Oct SKY express
17 Sep - 08 Oct SKY express
17 Sep - 01 Oct SKY express
17 Sep - 06 Oct SKY express

Also check the deals for one-way flights from Prague to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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