AirHint found the following cheapest return flights from Prague (PRG) to Karachi (KHI) in September 2025 (see full year).

Return flights

20 Sep - 11 Oct	Pegasus Airlines
20 Sep - 13 Oct	Pegasus Airlines
20 Sep - 05 Oct	Pegasus Airlines
18 Sep - 05 Oct	Pegasus Airlines
20 Sep - 04 Oct	Pegasus Airlines
17 Sep - 21 Sep	easyJet
04 Sep - 11 Sep	Pegasus Airlines
20 Sep - 12 Oct	Pegasus Airlines
20 Sep - 29 Sep	Pegasus Airlines
08 Sep - 27 Sep	Pegasus Airlines
06 Sep - 13 Sep	Pegasus Airlines
14 Sep - 06 Oct	Ryanair
10 Sep - 03 Oct	Pegasus Airlines

Also check the deals for one-way flights from Prague to Karachi in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Karachi in September from $210

Return flights