AirHint found the following cheapest return flights from Prague (PRG) to Los Angeles (LAX) in September 2025 (see full year).

Return flights

19 Sep - 29 Sep	Wizz Air UK
19 Sep - 08 Oct	Wizz Air UK
18 Sep - 17 Oct	Wizz Air UK
19 Sep - 01 Oct	Wizz Air UK
18 Sep - 22 Sep	Wizz Air UK
18 Sep - 21 Sep	easyJet
25 Sep - 28 Sep	easyJet
19 Sep - 21 Sep	Wizz Air UK
26 Sep - 12 Oct	easyJet
26 Sep - 19 Oct	easyJet
11 Sep - 26 Sep	easyJet
19 Sep - 23 Sep	Condor
12 Sep - 16 Sep	Condor
19 Sep - 07 Oct	Wizz Air UK
22 Sep - 28 Sep	Volotea
10 Sep - 17 Sep	Condor
16 Sep - 21 Oct	Condor
18 Sep - 02 Oct	Condor
29 Sep - 13 Oct	Condor
26 Sep - 13 Oct	Condor

Also check the deals for one-way flights from Prague to Los Angeles in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Los Angeles in September from $522

Return flights