AirHint found the following cheapest return flights from Prague (PRG) to Lisbon (LIS) in September 2025 (see full year).

Return flights

23 Sep - 30 Sep	easyJet
30 Sep - 07 Oct	Ryanair
30 Sep - 06 Oct	easyJet
18 Sep - 06 Oct	easyJet
18 Sep - 24 Sep	Ryanair
29 Sep - 01 Oct	easyJet
16 Sep - 01 Oct	easyJet
16 Sep - 24 Sep	Ryanair
28 Sep - 01 Oct	Ryanair
24 Sep - 06 Oct	Ryanair
18 Sep - 23 Sep	Ryanair
17 Sep - 24 Sep	Ryanair
25 Sep - 30 Sep	Ryanair
26 Sep - 30 Sep	easyJet
21 Sep - 24 Sep	Ryanair
25 Sep - 29 Sep	Ryanair
27 Sep - 04 Oct	easyJet
02 Sep - 09 Sep	SWISS
27 Sep - 07 Oct	easyJet
28 Sep - 04 Oct	easyJet

Also check the deals for one-way flights from Prague to Lisbon in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Lisbon in September from $174

Return flights