AirHint found the following cheapest return flights from Panama City (PTY) to Cancun (CUN) in October 2025 (see full year).

Return flights

15 Oct - 30 Oct	Avianca
18 Oct - 25 Oct	Avianca
01 Oct - 05 Oct	Avianca
23 Oct - 27 Oct	Avianca
13 Oct - 18 Oct	Avianca
09 Oct - 13 Oct	Aeromexico
03 Oct - 12 Oct	Aeromexico
09 Oct - 13 Oct	Copa	direct
16 Oct - 20 Oct	Copa	direct
23 Oct - 27 Oct	Copa	direct
31 Oct - 10 Nov	Avianca
31 Oct - 04 Nov	Avianca
31 Oct - 05 Nov	Avianca
31 Oct - 06 Nov	Copa
31 Oct - 10 Nov	Copa	direct
31 Oct - 06 Nov	Copa	direct
31 Oct - 04 Nov	Copa	direct
31 Oct - 05 Nov	Copa	direct

Also check the deals for one-way flights from Panama City to Cancun in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Cancun in October from $327

Return flights