Cheapest return flights from Panama City to Rome in December from $728

AirHint found the following cheapest return flights from Panama City (PTY) to Rome (FCO) in December 2025 (see full year).

Return flights

02 Dec - 24 Jan Air France
24 Dec - 24 Jan KLM
15 Dec - 22 Jan KLM
27 Dec - 12 Jan Air France
16 Dec - 22 Jan Air France
17 Dec - 22 Jan Air France
26 Dec - 05 Jan Air France
07 Dec - 20 Jan KLM
01 Dec - 08 Dec United
20 Dec - 17 Jan Avianca
16 Dec - 05 Jan Air France
08 Dec - 12 Dec KLM

Also check the deals for one-way flights from Panama City to Rome in December.

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