AirHint found the following cheapest return flights from Panama City (PTY) to Sao Paulo (GRU) in January 2026 (see full year).

Return flights

21 Jan - 23 Jan	Avianca
18 Jan - 25 Jan	Avianca
22 Jan - 05 Feb	Avianca
15 Jan - 08 Feb	Avianca
24 Jan - 02 Feb	Avianca
23 Jan - 02 Feb	Avianca
15 Jan - 18 Jan	Avianca
21 Jan - 23 Jan	Copa	direct
24 Jan - 02 Feb	Copa	direct
23 Jan - 02 Feb	Copa	direct
22 Jan - 05 Feb	Copa	direct
18 Jan - 25 Jan	Copa	direct
17 Jan - 05 Feb	Copa	direct
15 Jan - 08 Feb	Copa	direct
15 Jan - 18 Jan	Copa	direct
23 Jan - 01 Feb	Wingo

Also check the deals for one-way flights from Panama City to Sao Paulo in January.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Sao Paulo in January from $497

Return flights