AirHint found the following cheapest return flights from Panama City (PTY) to Sao Paulo (GRU) in October 2026 (see full year).

Return flights

25 Oct - 31 Oct	Avianca
29 Oct - 31 Oct	Avianca
01 Oct - 02 Oct	Avianca
01 Oct - 03 Oct	Avianca
30 Oct - 31 Oct	Avianca
27 Oct - 07 Nov	Avianca
27 Oct - 01 Nov	Avianca
25 Oct - 31 Oct	Copa	direct
01 Oct - 02 Oct	Copa	direct
01 Oct - 03 Oct	Copa	direct
27 Oct - 07 Nov	Copa	direct
27 Oct - 01 Nov	Copa	direct
30 Oct - 31 Oct	Copa	direct
29 Oct - 31 Oct	Copa	direct

Also check the deals for one-way flights from Panama City to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Sao Paulo in October from $522

Return flights