Cheapest return flights from Panama City to Guatemala City in December from $256

AirHint found the following cheapest return flights from Panama City (PTY) to Guatemala City (GUA) in December 2025 (see full year).

Return flights

05 Dec - 08 Dec Avianca
04 Dec - 08 Dec Avianca
25 Dec - 06 Jan Avianca
19 Dec - 23 Dec Avianca
03 Dec - 04 Jan Avianca
10 Dec - 12 Dec Avianca
15 Dec - 19 Dec Avianca
04 Dec - 08 Dec Copa direct
25 Dec - 06 Jan Copa direct
30 Dec - 03 Jan Copa direct
30 Dec - 03 Jan Avianca
15 Dec - 19 Dec Copa direct

Also check the deals for one-way flights from Panama City to Guatemala City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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