Cheapest return flights from Panama City to Guatemala City in September from $254

AirHint found the following cheapest return flights from Panama City (PTY) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

24 Sep - 27 Oct Avianca
28 Sep - 12 Oct Avianca
21 Sep - 28 Sep Avianca
23 Sep - 28 Sep Avianca
26 Sep - 28 Sep Avianca
24 Sep - 29 Sep Avianca
25 Sep - 28 Sep Avianca
19 Sep - 26 Sep Avianca
29 Sep - 16 Oct Avianca
21 Sep - 27 Sep Avianca
19 Sep - 26 Sep Copa direct

Also check the deals for one-way flights from Panama City to Guatemala City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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