Cheapest return flights from Panama City to Madrid in November from $714

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in November 2025 (see full year).

Return flights

05 Nov - 19 Nov Iberia direct
12 Nov - 18 Nov Air Europa direct
05 Nov - 14 Nov Air Europa direct
10 Nov - 14 Nov Air Europa direct
05 Nov - 18 Nov Air Europa direct
01 Nov - 10 Nov Avianca
11 Nov - 18 Nov Air Europa direct
01 Nov - 11 Nov Avianca
21 Nov - 24 Nov Air Europa direct
01 Nov - 15 Nov Turkish Airlines
21 Nov - 03 Dec Air France
25 Nov - 08 Dec United
21 Nov - 01 Dec Air France

Also check the deals for one-way flights from Panama City to Madrid in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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