Cheapest return flights from Panama City to Madrid in November from $717

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in November 2025 (see full year).

Return flights

06 Nov - 20 Nov KLM
16 Nov - 21 Nov Air France
14 Nov - 28 Nov Air France
16 Nov - 21 Nov Air Europa direct
15 Nov - 28 Nov Air France
13 Nov - 22 Nov Air Europa direct
05 Nov - 18 Nov Turkish Airlines
25 Nov - 02 Dec Turkish Airlines
16 Nov - 30 Nov Turkish Airlines
01 Nov - 10 Nov Avianca
16 Nov - 30 Nov Air Europa direct
21 Nov - 15 Dec Turkish Airlines
30 Nov - 14 Dec KLM
21 Nov - 15 Dec Air Europa direct
25 Nov - 02 Dec Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in November.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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