AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in February 2026 (see full year).

Return flights

17 Feb - 24 Feb	Air France
17 Feb - 09 Mar	Air France
17 Feb - 17 Mar	Air France
16 Feb - 24 Feb	KLM
28 Feb - 08 Mar	Air France
28 Feb - 16 Mar	Air France
19 Feb - 23 Feb	Air France
03 Feb - 10 Feb	Air France
16 Feb - 23 Feb	KLM
16 Feb - 25 Feb	KLM
17 Feb - 17 Mar	Air Europa	direct
28 Feb - 24 Mar	Air France
18 Feb - 24 Feb	KLM
02 Feb - 16 Mar	KLM
02 Feb - 17 Feb	KLM
11 Feb - 25 Feb	KLM
20 Feb - 26 Feb	Air France
25 Feb - 14 Mar	Turkish Airlines
17 Feb - 09 Mar	Air Europa	direct
18 Feb - 04 Mar	KLM

Also check the deals for one-way flights from Panama City to Madrid in February.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from Panama City to Madrid in February from $640

Return flights