Cheapest return flights from Panama City to Madrid in May from $703

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in May 2026 (see full year).

Return flights

15 May - 31 May Air Europa direct
23 May - 13 Jun Air Europa direct
17 May - 31 May Air Europa direct
17 May - 05 Jun Iberia direct
08 May - 18 May Air Europa direct
29 May - 14 Jun Iberia direct
19 May - 09 Jun Air Europa direct
29 May - 06 Jun Air Europa direct
15 May - 13 Jun Air Europa direct
08 May - 09 Jun Air Europa direct
30 May - 06 Jun Air Europa direct
15 May - 29 May Iberia direct
16 May - 13 Jun Air Europa direct
17 May - 27 May Iberia direct
02 May - 18 May Avianca
04 May - 30 Jun Air Europa direct
02 May - 18 May Air Europa direct
03 May - 13 May Air France
08 May - 31 May Avianca
03 May - 13 May Copa direct

Also check the deals for one-way flights from Panama City to Madrid in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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