AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in August 2025 (see full year).

Return flights

05 Aug - 22 Aug	Air France
07 Aug - 23 Aug	Iberia	direct
02 Aug - 06 Sep	Iberia	direct
15 Aug - 24 Aug	Air France
13 Aug - 22 Aug	Air France
15 Aug - 22 Aug	Air France
05 Aug - 22 Aug	Air Europa	direct
08 Aug - 20 Aug	Air France
06 Aug - 28 Aug	Air France
14 Aug - 31 Aug	Air France
01 Aug - 01 Sep	Air France
10 Aug - 23 Aug	Air France
20 Aug - 12 Sep	Copa
17 Aug - 01 Sep	Turkish Airlines
22 Aug - 15 Sep	Turkish Airlines
20 Aug - 10 Sep	Air France
17 Aug - 01 Sep	Iberia	direct
21 Aug - 03 Sep	Copa
21 Aug - 02 Sep	Copa
31 Aug - 16 Sep	Air France

Also check the deals for one-way flights from Panama City to Madrid in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Madrid in August from $718

Return flights