Cheapest return flights from Panama City to Santiago in December from $609

AirHint found the following cheapest return flights from Panama City (PTY) to Santiago (SCL) in December 2025 (see full year).

Return flights

07 Dec - 13 Dec Wingo
30 Dec - 12 Jan Wingo
21 Dec - 30 Dec Copa direct
07 Dec - 13 Dec Copa direct
19 Dec - 09 Jan Copa direct
30 Dec - 12 Jan Copa direct
29 Dec - 11 Jan Copa direct
20 Dec - 18 Jan Copa direct

Also check the deals for one-way flights from Panama City to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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