Cheapest return flights from Raleigh-durham to Rio Negro in May from $299

AirHint found the following cheapest return flights from Raleigh-durham (RDU) to Rio Negro (MDE) in May 2026 (see full year).

Return flights

22 May - 25 May Copa
28 May - 02 Jun United
11 May - 29 May Spirit Airlines
23 May - 26 May United
17 May - 29 May Spirit Airlines
11 May - 14 May Spirit Airlines
02 May - 11 May Spirit Airlines
14 May - 29 May Spirit Airlines
11 May - 23 May Spirit Airlines
23 May - 29 May Spirit Airlines
02 May - 14 May Spirit Airlines
11 May - 01 Jun Spirit Airlines
17 May - 04 Jun Spirit Airlines
17 May - 01 Jun Spirit Airlines
14 May - 04 Jun Spirit Airlines
23 May - 04 Jun Spirit Airlines
17 May - 05 Jun Spirit Airlines
14 May - 01 Jun Spirit Airlines
23 May - 01 Jun Spirit Airlines
29 May - 04 Jun Spirit Airlines

Also check the deals for one-way flights from Raleigh-durham to Rio Negro in May.

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