Cheapest return flights from Raleigh-durham to Panama City in September from $396

AirHint found the following cheapest return flights from Raleigh-durham (RDU) to Panama City (PTY) in September 2025 (see full year).

Return flights

18 Sep - 22 Sep Spirit Airlines
24 Sep - 29 Sep American Airlines
23 Sep - 28 Sep American Airlines
17 Sep - 21 Sep American Airlines
17 Sep - 21 Sep Copa direct
14 Sep - 19 Sep Copa direct
24 Sep - 29 Sep Copa direct
13 Sep - 18 Sep Frontier Airlines
11 Sep - 15 Sep American Airlines

Also check the deals for one-way flights from Raleigh-durham to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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