AirHint found the following cheapest return flights from Rome (ROM) to Cape Town (CPT) in October 2025 (see full year).

Return flights

09 Oct - 12 Oct	easyJet
09 Oct - 20 Oct	easyJet
08 Oct - 12 Oct	easyJet
01 Oct - 06 Oct	Wizz Air Malta
31 Oct - 08 Nov	Wizz Air Malta
26 Oct - 10 Nov	Wizz Air
03 Oct - 05 Oct	Ryanair
03 Oct - 10 Oct	Wizz Air Malta
02 Oct - 12 Oct	Wizz Air Malta
27 Oct - 09 Nov	Wizz Air Malta
26 Oct - 09 Nov	Wizz Air
29 Oct - 08 Nov	Wizz Air Malta
21 Oct - 27 Oct	Turkish Airlines
23 Oct - 27 Oct	Wizz Air Malta
19 Oct - 29 Oct	Qatar Airways
31 Oct - 02 Nov	SWISS
19 Oct - 01 Nov	Qatar Airways
22 Oct - 08 Nov	Wizz Air Malta
11 Oct - 01 Nov	easyJet

Also check the deals for one-way flights from Rome to Cape Town in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Cape Town in October from $647

Return flights