AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

14 Oct - 25 Oct	TAP
07 Oct - 28 Oct	TAP
08 Oct - 12 Oct	TAP
01 Oct - 13 Oct	TAP
16 Oct - 20 Oct	TAP
22 Oct - 25 Nov	TAP
27 Oct - 09 Nov	TAP
01 Oct - 02 Nov	TAP
09 Oct - 13 Oct	TAP
14 Oct - 21 Oct	TAP
15 Oct - 19 Oct	TAP
06 Oct - 14 Oct	TAP
30 Oct - 09 Nov	TAP
30 Oct - 13 Nov	TAP
30 Oct - 07 Nov	TAP
30 Oct - 19 Nov	TAP
09 Oct - 24 Oct	TAP
31 Oct - 02 Nov	TAP
31 Oct - 09 Nov	TAP
30 Oct - 06 Nov	Air Europa

Also check the deals for one-way flights from Rome to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in October from $688

Return flights