AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

01 Dec - 11 Dec	TAP
01 Dec - 10 Dec	TAP
01 Dec - 08 Dec	TAP
02 Dec - 10 Dec	TAP
01 Dec - 17 Dec	Air Europa
06 Dec - 13 Dec	Air Europa
06 Dec - 19 Jan	TAP
01 Dec - 19 Dec	Air Europa
10 Dec - 22 Dec	TAP
08 Dec - 11 Dec	Air Europa
11 Dec - 24 Jan	TAP
01 Dec - 13 Jan	TAP
02 Dec - 10 Dec	LATAM Airlines Group	direct
17 Dec - 12 Jan	Air Canada
06 Dec - 19 Jan	LATAM Airlines Group	direct
11 Dec - 24 Jan	ITA Airways	direct
23 Dec - 21 Jan	Iberia
10 Dec - 05 Jan	TAP
27 Dec - 21 Jan	TAP
19 Dec - 23 Jan	TAP

Also check the deals for one-way flights from Rome to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in December from $586

Return flights