AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in April 2026 (see full year).

Return flights

15 Apr - 27 May	TAP
16 Apr - 23 Apr	TAP
28 Apr - 26 May	SWISS
05 Apr - 23 Apr	ITA Airways	direct
27 Apr - 23 May	TAP
01 Apr - 13 Apr	LATAM Airlines Group
03 Apr - 24 Apr	ITA Airways	direct
01 Apr - 05 Apr	ITA Airways	direct
14 Apr - 28 Apr	SWISS
12 Apr - 26 Apr	ITA Airways	direct
16 Apr - 23 Apr	ITA Airways	direct
07 Apr - 14 Apr	Ethiopian Airlines
17 Apr - 28 Apr	Lufthansa
24 Apr - 18 May	Lufthansa
01 Apr - 10 May	TAP
27 Apr - 10 May	TAP
23 Apr - 05 May	Iberia
28 Apr - 05 May	Iberia
28 Apr - 08 May	Iberia
15 Apr - 27 May	ITA Airways	direct

Also check the deals for one-way flights from Rome to Sao Paulo in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in April from $699

Return flights