AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

10 Sep - 22 Sep	TAP
08 Sep - 22 Sep	TAP
02 Sep - 10 Sep	TAP
03 Sep - 14 Sep	TAP
12 Sep - 19 Sep	TAP
09 Sep - 16 Sep	TAP
09 Sep - 30 Sep	TAP
17 Sep - 28 Sep	TAP
10 Sep - 22 Sep	LATAM Airlines Group	direct
01 Sep - 14 Sep	TAP
22 Sep - 01 Oct	TAP
23 Sep - 12 Oct	British Airways
23 Sep - 10 Oct	British Airways
25 Sep - 12 Oct	British Airways
20 Sep - 05 Oct	Air Europa
26 Sep - 05 Oct	British Airways
22 Sep - 12 Oct	Air Europa
20 Sep - 05 Oct	LATAM Airlines Group	direct
28 Sep - 05 Oct	Delta
25 Sep - 02 Oct	Delta

Also check the deals for one-way flights from Rome to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in September from $586

Return flights