Cheapest return flights from Rome to Prague in September from $51

Best time to book flights for Rome (ROM) to Prague (PRG) flights at AirHint

AirHint found the following cheapest return flights from Rome (ROM) to Prague (PRG) in September 2025 (see full year).

Return flights

10 Sep - 24 Sep Ryanair direct
17 Sep - 24 Sep Ryanair direct
10 Sep - 22 Sep Ryanair direct
17 Sep - 01 Oct Ryanair direct
10 Sep - 15 Sep Ryanair direct
17 Sep - 22 Sep Ryanair direct
18 Sep - 24 Sep Ryanair direct
09 Sep - 24 Sep Wizz Air Malta direct
04 Sep - 24 Sep Wizz Air Malta direct
16 Sep - 24 Sep Wizz Air Malta direct
18 Sep - 08 Oct Ryanair direct
18 Sep - 01 Oct Ryanair direct
16 Sep - 01 Oct Wizz Air Malta direct
24 Sep - 24 Sep Wizz Air Malta direct
24 Sep - 08 Oct Wizz Air Malta direct
24 Sep - 01 Oct Wizz Air Malta direct
12 Sep - 01 Oct Ryanair direct
11 Sep - 01 Oct Ryanair direct
13 Sep - 01 Oct Ryanair direct
20 Sep - 08 Oct Ryanair direct

Also check the deals for one-way flights from Rome to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague