AirHint found the following cheapest return flights from Rome (ROM) to Istanbul (SAW) in October 2025 (see full year).

Return flights

29 Oct - 23 Nov	Wizz Air Malta
24 Oct - 15 Nov	Pegasus Airlines
25 Oct - 30 Oct	AJet
25 Oct - 31 Oct	AJet
24 Oct - 06 Nov	AJet
31 Oct - 07 Nov	Ryanair
21 Oct - 31 Oct	Wizz Air Malta
30 Oct - 01 Nov	Ryanair
31 Oct - 05 Nov	Ryanair
29 Oct - 06 Nov	Wizz Air
26 Oct - 06 Nov	Wizz Air Malta
21 Oct - 30 Oct	Ryanair
24 Oct - 31 Oct	AJet
28 Oct - 30 Oct	easyJet
21 Oct - 18 Nov	Pegasus Airlines	direct
27 Oct - 06 Nov	Wizz Air
22 Oct - 23 Oct	AJet	direct
21 Oct - 23 Oct	Ryanair
23 Oct - 27 Oct	Wizz Air Malta
28 Oct - 31 Oct	Ryanair

Also check the deals for one-way flights from Rome to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Istanbul in October from $163

Return flights