AirHint found the following cheapest return flights from Rome (ROM) to Santiago (SCL) in October 2026 (see full year).

Return flights

22 Oct - 06 Nov	Delta
03 Oct - 18 Oct	Turkish Airlines
17 Oct - 01 Nov	Turkish Airlines
05 Oct - 17 Oct	Turkish Airlines
30 Oct - 14 Nov	Turkish Airlines
01 Oct - 17 Oct	Turkish Airlines
29 Oct - 12 Nov	Delta

Also check the deals for one-way flights from Rome to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in October from $877

Return flights