AirHint found the following cheapest return flights from Rome (ROM) to Santiago (SCL) in November 2025 (see full year).

Return flights

17 Nov - 27 Nov	Iberia
24 Nov - 02 Dec	Iberia
16 Nov - 27 Nov	Delta
07 Nov - 25 Nov	Delta
07 Nov - 23 Nov	Delta
06 Nov - 07 Dec	Delta
28 Nov - 16 Dec	Iberia
26 Nov - 06 Dec	Iberia
13 Nov - 08 Dec	Delta
10 Nov - 08 Dec	Delta
12 Nov - 26 Nov	Delta
12 Nov - 24 Nov	Delta
03 Nov - 17 Nov	Air Canada
29 Nov - 13 Dec	Iberia
29 Nov - 14 Dec	Iberia
17 Nov - 11 Dec	Air France
04 Nov - 06 Nov	Delta
17 Nov - 23 Nov	Air France
20 Nov - 27 Nov	Ryanair

Also check the deals for one-way flights from Rome to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in November from $783

Return flights