AirHint found the following cheapest return flights from Rome (ROM) to Santander (SDR) in April 2026 (see full year).

Return flights

09 Apr - 13 Apr	Vueling Airlines
08 Apr - 13 Apr	Vueling Airlines
08 Apr - 12 Apr	Vueling Airlines
09 Apr - 12 Apr	Vueling Airlines
10 Apr - 13 Apr	Vueling Airlines
04 Apr - 13 Apr	Vueling Airlines
10 Apr - 12 Apr	Vueling Airlines
04 Apr - 12 Apr	Vueling Airlines
30 Apr - 03 May	ITA Airways
04 Apr - 05 Apr	Vueling Airlines
06 Apr - 13 Apr	Vueling Airlines
23 Apr - 03 May	Vueling Airlines
16 Apr - 03 May	Vueling Airlines

Also check the deals for one-way flights from Rome to Santander in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santander in April from $134

Return flights