AirHint found the following cheapest return flights from San Salvador (SAL) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

30 Sep - 05 Oct	Avianca	direct
27 Sep - 30 Sep	Copa
20 Sep - 27 Sep	Copa
15 Sep - 20 Sep	Copa
16 Sep - 17 Sep	Copa
10 Sep - 14 Sep	Copa
04 Sep - 08 Sep	Copa
29 Sep - 08 Oct	Copa
04 Sep - 08 Sep	Avianca	direct
17 Sep - 21 Sep	Copa
12 Sep - 17 Sep	Copa
12 Sep - 16 Sep	Copa

Also check the deals for one-way flights from San Salvador to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Salvador to Rio Negro in September from $279

Return flights