AirHint found the following cheapest return flights from San Diego (SAN) to Rome (FCO) in October 2025 (see full year).

Return flights

20 Oct - 27 Oct	Air Canada
21 Oct - 29 Oct	Air Canada
22 Oct - 29 Oct	United
25 Oct - 11 Nov	British Airways
07 Oct - 14 Oct	United
16 Oct - 28 Oct	Air Canada
17 Oct - 24 Oct	United
20 Oct - 26 Oct	Air Canada
12 Oct - 19 Oct	United
02 Oct - 09 Oct	United
27 Oct - 03 Nov	United

Also check the deals for one-way flights from San Diego to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Diego to Rome in October from $523

Return flights