AirHint found the following cheapest return flights from San Diego (SAN) to Rome (FCO) in December 2025 (see full year).

Return flights

09 Dec - 16 Dec	Brussels Airlines
09 Dec - 14 Dec	Brussels Airlines
11 Dec - 21 Jan	Lufthansa
14 Dec - 14 Jan	British Airways
07 Dec - 14 Dec	Lufthansa
13 Dec - 25 Dec	Air Canada
31 Dec - 09 Jan	United
29 Dec - 08 Jan	United
30 Dec - 07 Jan	Lufthansa
04 Dec - 23 Dec	United
16 Dec - 26 Dec	United
31 Dec - 06 Jan	Lufthansa
31 Dec - 05 Jan	Lufthansa
20 Dec - 11 Jan	Frontier Airlines
20 Dec - 10 Jan	Frontier Airlines
19 Dec - 11 Jan	Alaska Airlines
19 Dec - 22 Dec	Aer Lingus
17 Dec - 30 Dec	WestJet

Also check the deals for one-way flights from San Diego to Rome in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Diego to Rome in December from $408

Return flights