AirHint found the following cheapest return flights from San Diego (SAN) to Madrid (MAD) in October 2025 (see full year).

Return flights

14 Oct - 31 Oct	Air Canada
14 Oct - 21 Oct	United
21 Oct - 28 Oct	Lufthansa
08 Oct - 23 Oct	Air France
28 Oct - 06 Nov	KLM
07 Oct - 16 Oct	Air Canada
15 Oct - 30 Oct	Lufthansa
15 Oct - 22 Oct	Air France
01 Oct - 16 Oct	Iberia
14 Oct - 05 Nov	Lufthansa
30 Oct - 13 Nov	United
26 Oct - 09 Nov	United
22 Oct - 29 Oct	United
16 Oct - 23 Oct	United
29 Oct - 22 Nov	British Airways
28 Oct - 04 Nov	United
26 Oct - 02 Nov	United
30 Oct - 03 Nov	Air Canada
30 Oct - 29 Nov	Delta

Also check the deals for one-way flights from San Diego to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Diego to Madrid in October from $572

Return flights