AirHint found the following cheapest return flights from San Pedro Sula (SAP) to Panama City (PTY) in September 2025 (see full year).

Return flights

27 Sep - 05 Oct	Avianca
26 Sep - 05 Oct	Avianca
28 Sep - 05 Oct	Avianca
30 Sep - 10 Oct	Avianca
13 Sep - 28 Sep	Avianca
13 Sep - 28 Sep	Copa	direct
28 Sep - 10 Oct	Avianca
11 Sep - 05 Oct	Avianca
11 Sep - 06 Oct	Avianca
26 Sep - 05 Oct	Copa	direct
11 Sep - 05 Oct	Copa	direct
11 Sep - 06 Oct	Copa	direct

Also check the deals for one-way flights from San Pedro Sula to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Pedro Sula to Panama City in September from $406

Return flights