AirHint found the following cheapest return flights from Santiago (SCL) to Asuncion (ASU) in October 2025 (see full year).

Return flights

26 Oct - 31 Oct	LATAM Airlines Group
31 Oct - 03 Nov	LATAM Airlines Group
26 Oct - 31 Oct	LATAM Airlines Group	direct
30 Oct - 02 Nov	Aerolineas Argentinas
29 Oct - 30 Oct	JetSmart
28 Oct - 30 Oct	JetSmart
28 Oct - 02 Nov	JetSmart
27 Oct - 30 Oct	JetSmart
29 Oct - 16 Nov	JetSmart
27 Oct - 02 Nov	JetSmart
28 Oct - 16 Nov	JetSmart
31 Oct - 16 Nov	JetSmart
30 Oct - 02 Nov	LATAM Airlines Group	direct
30 Oct - 16 Nov	JetSmart
27 Oct - 16 Nov	JetSmart
20 Oct - 25 Oct	JetSmart
20 Oct - 24 Oct	JetSmart
20 Oct - 30 Oct	JetSmart
20 Oct - 26 Oct	JetSmart

Also check the deals for one-way flights from Santiago to Asuncion in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Asuncion in October from $389

Return flights