AirHint found the following cheapest return flights from Santiago (SCL) to Cancun (CUN) in October 2025 (see full year).

Return flights

20 Oct - 30 Oct	Sky Airline
20 Oct - 18 Nov	Sky Airline
22 Oct - 29 Oct	Sky Airline
15 Oct - 05 Nov	Sky Airline
14 Oct - 21 Oct	Sky Airline
14 Oct - 23 Oct	Sky Airline
16 Oct - 23 Oct	Sky Airline
15 Oct - 22 Oct	Sky Airline
01 Oct - 07 Oct	Sky Airline
29 Oct - 06 Nov	Sky Airline
28 Oct - 06 Nov	Sky Airline
22 Oct - 01 Nov	Sky Airline
23 Oct - 01 Nov	Sky Airline
19 Oct - 26 Oct	Avianca
17 Oct - 26 Oct	Arajet
24 Oct - 04 Nov	Arajet
24 Oct - 05 Nov	Arajet
24 Oct - 28 Oct	Arajet
20 Oct - 20 Nov	Arajet
27 Oct - 09 Nov	Arajet

Also check the deals for one-way flights from Santiago to Cancun in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Cancun

Cheap car rent in Cancun

Cheapest return flights from Santiago to Cancun in October from $377

Return flights