AirHint found the following cheapest return flights from Santiago (SCL) to Cancun (CUN) in September 2025 (see full year).

Return flights

30 Sep - 08 Oct	Sky Airline
29 Sep - 08 Oct	Sky Airline
08 Sep - 14 Sep	Arajet
05 Sep - 16 Sep	Sky Airline
03 Sep - 11 Sep	Sky Airline
04 Sep - 11 Sep	Sky Airline
05 Sep - 10 Sep	Sky Airline
24 Sep - 01 Oct	Sky Airline
28 Sep - 05 Oct	Avianca
19 Sep - 30 Sep	Arajet
23 Sep - 30 Sep	Sky Airline
20 Sep - 30 Sep	Sky Airline
10 Sep - 18 Sep	Arajet
22 Sep - 28 Sep	Sky Airline
26 Sep - 05 Oct	Copa
21 Sep - 06 Oct	Sky Airline

Also check the deals for one-way flights from Santiago to Cancun in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Cancun in September from $408

Return flights