AirHint found the following cheapest return flights from Santiago (SCL) to Rome (FCO) in September 2025 (see full year).

Return flights

26 Sep - 12 Oct	Iberia
06 Sep - 26 Sep	LATAM Airlines Group
05 Sep - 29 Sep	LATAM Airlines Group
04 Sep - 30 Sep	Avianca
06 Sep - 29 Sep	LATAM Airlines Group
27 Sep - 12 Oct	Aerolineas Argentinas
02 Sep - 29 Sep	LATAM Airlines Group
02 Sep - 30 Sep	LATAM Airlines Group
01 Sep - 25 Sep	LATAM Airlines Group
02 Sep - 18 Sep	LATAM Airlines Group
05 Sep - 27 Sep	LATAM Airlines Group
05 Sep - 19 Sep	LATAM Airlines Group
23 Sep - 22 Oct	Air France
19 Sep - 17 Oct	Avianca
28 Sep - 18 Oct	Avianca
11 Sep - 07 Oct	Air France
30 Sep - 15 Oct	Condor
12 Sep - 04 Oct	Avianca
23 Sep - 13 Oct	Turkish Airlines

Also check the deals for one-way flights from Santiago to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rome in September from $1021

Return flights