AirHint found the following cheapest return flights from Santiago (SCL) to Guatemala City (GUA) in April 2026 (see full year).

Return flights

17 Apr - 20 Apr	Copa
17 Apr - 27 Apr	Copa
24 Apr - 27 Apr	Copa
18 Apr - 27 Apr	Copa
17 Apr - 28 Apr	Copa
18 Apr - 28 Apr	Copa
16 Apr - 23 Apr	Copa
17 Apr - 24 Apr	Copa
17 Apr - 04 May	Copa
17 Apr - 27 May	Copa
24 Apr - 04 May	Copa
25 Apr - 15 May	Copa
16 Apr - 06 May	Copa
10 Apr - 20 Apr	Copa
06 Apr - 12 Apr	LATAM Airlines Group

Also check the deals for one-way flights from Santiago to Guatemala City in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Guatemala City in April from $447

Return flights