Cheapest return flights from Santiago to Guayaquil in December from $514

AirHint found the following cheapest return flights from Santiago (SCL) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

31 Dec - 04 Jan Copa
31 Dec - 08 Jan Copa
27 Dec - 02 Jan Copa
25 Dec - 03 Jan Copa
25 Dec - 04 Jan Copa
26 Dec - 11 Jan Copa
27 Dec - 17 Jan Copa
25 Dec - 03 Jan LATAM Airlines Group direct
24 Dec - 06 Jan LATAM Airlines Group direct
26 Dec - 11 Jan LATAM Airlines Group direct

Also check the deals for one-way flights from Santiago to Guayaquil in December.

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