Cheapest return flights from Santiago to Guayaquil in December from $333

AirHint found the following cheapest return flights from Santiago (SCL) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

15 Dec - 27 Dec LATAM Airlines Group
19 Dec - 28 Dec LATAM Airlines Group
18 Dec - 04 Jan LATAM Airlines Group
20 Dec - 05 Jan LATAM Airlines Group
23 Dec - 14 Jan LATAM Airlines Group
23 Dec - 11 Jan LATAM Airlines Group

Also check the deals for one-way flights from Santiago to Guayaquil in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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