AirHint found the following cheapest return flights from Santiago (SCL) to Lisbon (LIS) in September 2025 (see full year).

Return flights

26 Sep - 05 Oct	JetSmart
22 Sep - 07 Oct	JetSmart
28 Sep - 08 Oct	Iberia
17 Sep - 28 Sep	LATAM Airlines Group
08 Sep - 15 Sep	LATAM Airlines Group
24 Sep - 05 Oct	JetSmart
16 Sep - 29 Sep	Avianca
09 Sep - 16 Sep	LATAM Airlines Group
10 Sep - 23 Sep	Sky Airline
15 Sep - 08 Oct	Avianca
17 Sep - 05 Oct	LATAM Airlines Group
11 Sep - 18 Oct	LATAM Airlines Group
06 Sep - 20 Sep	Avianca
10 Sep - 26 Sep	LATAM Airlines Group
13 Sep - 05 Oct	Sky Airline
13 Sep - 28 Sep	Sky Airline
14 Sep - 28 Sep	LATAM Airlines Group
13 Sep - 18 Oct	Sky Airline
13 Sep - 20 Sep	Sky Airline

Also check the deals for one-way flights from Santiago to Lisbon in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Lisbon in September from $1011

Return flights